1992 & Older Publications

Highlights
* = co-first author, † = corresponding author

The structure determination of monoclinic canine parvovirus

Tsao J, Chapman M S, Wu H, Agbandje M, Keller W, Rossmann M G. Acta Crystallogr. (1992). PDF

The three-dimensional structure of the single stranded DNA canine parvovirus has been determined to 3.25 Å resolution. Monoclinic crystals belonging to space group P21 (a = 263.1, b = 348.9, c=267.2.A,, fl =90.82 Å) were selected for data collection using primarily the Cornell High Energy Synchrotron Source and oscillation photography. There was one icosahedral particle per crystallographic asymmetric unit... Read More

Molecular replacement real space averaging

Rossmann M G†, McKenna R, Tong L, Xia D, Dai J, Wu H, Choi H, Lynch R E. J. Appl. Crystallogr. (1992). PDF 

Structure determination of macromolecules often depends on phase improvement and phase extension by use of real-space averaging of electron density related by noncrystallographic symmetry. Although techniques for such procedures have been described previously modern computer architecture and experience with
these methods have suggested changes and improvements. Two unit cells... Read More

Crystallization of cauliflower mosaic virus

Gong Z X, Wu H, Cheng R H, Hull R, Rossmann M G†. Virology (1990). PDF 

Caulimoviruses (I) were the first reported plant viruses with a double-stranded DNA genome. The particles have a diameter of around 500 A and, at least in the case of the type member of the group cauliflower mosaic virus (CaMV), are composed primarily of about 420 copies of a protein with a molecular weight of around 40,000 (2-4). The CaMV coat protein is derived from open reading frame (ORF)... Read More

white block.jpg
harvard medical school logo.png
white block.jpg
bch logo.png
white block.jpg
df hcc logo.png

Boston Children's Hospital

3 Blackfan Circle, Room 3024

Boston, MA 02115
617-713-8167

Copyright © 2020 The President and Fellows of Harvard College